Vitamin c liposome encapsulated? Cell membranes are typically composed of a phospholipid bilayer. This bilayer contains a hydrophilic, or “water loving” head group, and a lipophilic, or “fat loving” tail, which is composed of a long hydrocarbon chain that repels by water. Phospholipids are therefore classified as amphipathic molecules as a result of the presence of both hydrophilic and hydrophobic components.
Recent studies show a strong link to vitamin C levels and regular immune function. Most scientists will admit, we don’t know all the benefits as of yet. Very high doses of vitamin C (sometimes called megadoses) are showing surprising results for helping boost the body’s immune system. Vitamin C raises hydrogen peroxide levels that pathogens and unhealthy cells are vulnerable to, leaving healthy human cells, who tolerate the higher peroxide levels, unharmed. Vitamin C looks to be the body’s natural defense against bad actors, and we are only just discovering the benefits.
Until recently intravenous delivery of vitamin C has proven to be the most effective route for absorption, but this method of delivery is both costly and impractical. However, Liposomal vitamin C allows you to take vitamin C orally ensuring it reaches the cells where it is needed. A substantial number of studies have already documented the versatile advantages of using Liposomes for targeted site-specific delivery and efficient absorption through cells. Discover extra info on What is a liposome.
A study showed that PEGylated liposomes of mitomycin C were captured by cells and collected at the target site due to enhanced permeability and retention (EPR) effect.40 Recently, folate-modified doxorubicin-loaded nanoliposomes were shown to effectively inhibit the growth of B16F10 melanoma cells. The folate-modified liposomes improved antitumor efficacy and reduced systemic toxicity of doxorubicin.41 Thus, combination of CUR and liposomes should enhance the stability, bioavailability, targeting property and anticancer efficacy of CUR. The purpose of this review is to introduce the preparation method and application of liposomes in CUR and their effects on cancer therapy.
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